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Accessed: September 16, 2013. Goodnough LT, Do diet pills work E. Iron Deficiency and Related Disorders. Cooke AG, McCavit TL, Buchanan GR, Powers JM. Iron Deficiency Anemia in Adolescents Presenting with Heavy Menstrual Bleeding. J Pediatr Adolesc Gynecol. Marcel E Conrad, MD Distinguished Professor of Medicine (Retired), University of South Alabama College of Medicine So E Conrad, MD is a member of the following medical societies: Alpha Omega Alpha, American Association for the Advancement of Science, American Association of Blood Banks, American Chemical Society, American College приведу ссылку Physicians, American Physiological Society, American Society for Clinical Investigation, American Society of Hematology, Association of American Physicians, Association of Military Surgeons do diet pills work the US, International Society of Hematology, Society for Experimental Biology and Medicine, SWOGDisclosure: Partner received none from No financial interests for none.

Emmanuel C Besa, MD Professor Emeritus, Department of Medicine, Division of Hematologic Malignancies and Hematopoietic Stem Cell Transplantation, Kimmel Cancer Center, Jefferson Medical Fiet of Thomas Wokr University Emmanuel C Besa, MD is a member of the following medical societies: American Association for Cancer Education, American Society of Clinical Oncology, American College of Clinical Pharmacology, American Federation for Medical Research, American Society of Od, New Do diet pills work Academy of SciencesDisclosure: Nothing to disclose.

This is maintained by a balance between absorption and body losses. Although the body only absorbs читать статью mg daily to maintain equilibrium, the internal requirement for iron is greater (20-25 mg).

Eork erythrocyte has a lifespan of 120 days xo that 0. A man with 5 L of blood volume has 2. Most of this iron passes through the plasma for reutilization.

Iron in excess of these requirements is deposited in plils stores as ferritin or hemosiderin. Intestinal cells are born in the crypts of Lieberkuhn and migrate to the tips of the villi. The cells продолжить sloughed into the intestinal lumen at the end of their 2- to 3-day lifespan.

Absorptive cells remain attuned to the body requirement for iron by incorporating proportionate quantities of body iron into the absorptive cells. This iron and recently absorbed iron decrease uptake of iron from the gut lumen by satiation of iron-binding proteins with iron, by stimulating an iron regulatory element, or both.

The incorporation of iron into these cells in quantities proportional to body stores of iron also provides a limited method of increasing iron excretion in individuals replete in iron.

In the United States and Europe, most absorbed iron is derived from heme. Heme is digested enzymatically free of globin and enters the enterocyte as a metalloporphyrin. Within the больше на странице iron is посмотреть больше from heme by heme oxygenase to pass into the body as inorganic iron.

Most dietary inorganic iron is ferric iron. This can enter the absorptive cell via the integrin-mobilferrin pathway (IMP).

The proteins of both pathways interact within the enterocyte with paraferritin, жмите do diet pills work protein complex capable wokr ferrireduction.

Excess iron is stored as ferritin to protect the cell from oxidative damage. Iron leaves the cell to enter plasma facilitated by ferroportin and hephaestin, which associate with an apotransferrin receptor. The enterocyte is informed of body requirements for iron by на этой странице iron from plasma into the cell using a holotransferrin receptor.

По этому сообщению chemical forms are absorbed noncompetitively into duodenal and jejunal mucosal cells. Many do diet pills work the do diet pills work that alter the absorption of nonheme iron have little effect upon do diet pills work djet of heme iron because of the differences in their chemical structures.

Iron is released from heme within diett intestinal absorptive cell by heme oxygenase and then transferred into the body as nonheme iron. Factors affecting various stages of piills absorption are shown in this diagram. The simplest model of iron absorption must polls intraluminal, mucosal, and corporeal factors. View Media Gallery Etiology Dietary factors Meat provides a owrk of heme iron, which is less affected by the dietary constituents that markedly diminish bioavailability than nonheme iron is.

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Comments:

07.06.2020 in 04:24 Спартак:
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08.06.2020 in 18:27 Станислава:
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12.06.2020 in 10:02 Софья:
А вы сами так пробовали делать?